Saudi Journal of Pathology and Microbiology (SJPM)
Volume-4 | Issue-02 | 77-81
Original Research Article
Clinico-Pathological Spectrum of Endometrium in Abnormal Uterine Bleeding - A Cross Sectional Study
Dr. Anita B Sajjanar
Published : Feb. 18, 2019
Abstract
The term “menstruation” is derived from the Latin word “menstruus” meaning “monthly”. Sir John Williams stated that
menstruation is a cyclical process, which begins at cessation of menstrual flow, passes through the developmental
changes of mucus membrane of the uterus and ends with the cessation of the next following menstruation” [1].
Objective-To evaluate histopathology of endometrium in abnormal uterine bleeding. The endometrial samples
(endometrial curettage/ biopsy and hysterectomy specimens) sent to pathology laboratory were analysed. These
specimens are fixed in 10% formalin and gross morphology was recorded. A detailed histological study was carried out
and the findings were noted. Statistical analysis was done. In the present study maximum number of patients (46 cases)
belongs to an age group of 31-40 years followed by 34 cases belongs to an age group of 41-50 years and 12 cases belongs
to 21-30 year age group (Table-1). In the present study maximum number of patients (58 cases) presented with a
symptom of heavy bleeding followed by Inter-menstrual Bleeding was seen in 24 patients and Heavy & prolonged
bleeding was seen in 6 cases (Table-2). Proliferative phase was the most common histo-pathological finding accounting
for 41% followed by secretory phase accounting for 24%, simple hyperplasia without atypia accounting for 17%,
complex hyperplasia with atypia in 8%, endometrial polyp & Disordered Proliferative endometrium in 3%, endometrial
adenocarcinoma 1% (Table-3). Histopathological evaluation of endometrial sample in women with AUB has a vital role
in the diagnosis of different histological patterns. Therefore, histo-pathological examination is of paramount importance
particularly in women of peri-menopausal and post-menopausal age groups who present with AUB.