Saudi Journal of Pathology and Microbiology (SJPM)
Volume-4 | Issue-02 | 64-67
Original Research Article
Cytology and Histopathology Correlation of Breast Lesions
Dr. K. Ramakrishna Reddy, Dr. M. M. Poornima
Published : Feb. 10, 2019
Abstract
Benign breast diseases are common in young females in the second and third decade of life. Most common presentation
is painless lump in the breast. Clinical and cytological correlation is essential for definitive diagnosis and early treatment
of the lesions. Fine Needle Aspiration Cytology (FNAC) is a popular technique utilized in the diagnosis of palpable
masses anywhere in the body, it is sensitive and specific, expedient, economical and safe and less time consuming
without much discomfort to the patient. The aim of this study is to analyze and correlate the diagnosis of breast lesions
on cytology with histopathology. This is a retrospective cum prospective study which includes 468 cases of palpable
breast masses. The chief complaint was lump in the breast, pain in the breast and/or discharge from the nipple. Patients’
ultrasound findings were noted. FNAC was performed by using 23 gauge needle attached to 5 ml or 10ml disposable
syringe. For histopathological examination tissue was grossed and representative areas were taken and processed for slide
preparation and staining. Slides were examined under light microscope and the findings were correlated with FNAC
findings. The study included 468 breast masses / cases, which were diagnosed on cytology. Most of the cases in this
study were in the age group 20- 29 years (157 cases). The size of the lesion varied from 1.0 cm to 7.6 cm in the largest
plane, number of swellings in a single breast varied from one to eight. Largest numbers of multiple fibroadenomas (both
breast) were 16 of varying sizes. Most of the lesions were noted in the left breast than right breast. The accuracy of the
FNAC is 97.88 % in this study.