Production and supply of pathogen and toxic chemical free water is the preliminary aim of water treatment. The natural killing property of bacteriophages makes them the most prominent tool in eliminating unwanted bacteria, making them ideal candidate in water treatment research. In this study phage formulations against multidrug resistant E. coli KP005067 were fabricated by immobilizing them in broth, activated charcoal and alginate beads. The cross section of the phage formulation was analysed using Confocal Raman Microscope and the disinfection study was carried out in batch and packed bed reactor. The phage formulations remained stable for almost 4-8 and 3-5 months at 4oC and 30oC respectively. The batch reduction study using phage connoted the order of host reduction as phage-charcoal > phagebroth > phage-bead. Further more, the disinfection study using packed bed reactor showed 100 and 97% host reduction using phage-charcoal and phage-bead respectively. At the same time, there was concomitant increase in the phage population in the packed bed-reactor indicating that the phage formulations are highly potent in killing bacterial pathogen in water.