Background: The L5/S1 intervertebral foramen which houses the largest nerve trunk in the lumbosacral region is the smallest in the vertebral column, and studies on spinal health has revealed that certain clinical conditions of the lower back and the predisposition to them such as spondylosis, spondylolysis and lower back pain may be associated with anatomical variations in the size of the bony components in this region. The study seeks to evaluate normal measurement values of the LSA, LSA and LLD of the spine of healthy female Nigerians, and find out if there exists significant associations between these normal values and with respect to age. A secondary purpose is to provide an indirect method for estimating the epidural space by measuring the depth of lumbar lordosis (LLD). Materials and Methods: Lateral x-ray films of the lumbar and lumbosacral spine of 45 informed volunteers who met the inclusion criteria were studied with respect to the LLD, LLA and LLA using standard radiologic procedures. Results and Discussion: Lumbosacral parameters were 32.04±6.080, 49.84±8.260 and 3.36±0.45cm for LSA, LLA and LLD respectively. Average values of spine parameters varied significantly with age; except for LSA, significant differences were found between age groups. Mean LLA was significant between age group 18-22 and 23-27 years, while mean LLD was significant between age group 18-22 and 23-27, as well as 18-22 and 33-37 years. Statistically significant correlation (at P < 0.05) was found between LLA and age and also between LLD and age. On the average, the size and shape of lumbosacral curve dimensions as determined by lateral x-ray in healthy female Nigerians, fall within the range considered normal and are significantly influenced by age. Conclusion: The findings of this research will be helpful to physicians in the management of low back and also in drawing treatment plans for other back related conditions.