Saudi Journal of Pathology and Microbiology (SJPM)
Volume-4 | Issue-01 | 21-25
Original Research Article
Endometrial Biopsy in Abnormal Uterine Bleeding: An Effective Tool in Minimizing Unnecessary Hysterectectomies
Dr. Gitika Hyanki, Dr. Prabhat Pant, Dr. Ghazala Rizvi
Published : Jan. 30, 2019
Abstract
Introduction: Abnormal uterine bleeding is the most common presentation amongst women of all age groups attending
the gynecology OPD. The etiology of AUB varies depending on the age group. Histopathological study of endometrial
biopsies by light microscope is considered the gold standard for diagnosing the endometrial pathology of AUB. Aims &
Objective: The aims and objective of this study is to determine histopathological patterns seen in endometrial biopsies of
women who presented with AUB. Material and methods: The study was carried out in the Department of Pathology in
Government Medical College Haldwani from January 2008 to January 2018. Biopsy sections underwent proper
processing and stained with hematoxylin and eosin and were observed under microscope. Relevant patient details were
collected from departmental records. Result: Total of 505 specimens of endometrial biopsies were studied. Maximum
(47%) patients were between 36-45 years. Commonest pathology was disordered proliferative phase (20%). 11% showed
hormone related changes. Hyperplasia was observed in 7%. Endometrial polyps were seen in 2%, Endometritis was
found in 2% which included 2 cases of tubercular pathology. Endometrial carcinoma was seen in 2%. Conclusion:
Maximum patients in our study belonged to the perimenopausal age group. Disordered proliferative pattern was the most
common pathology observed. Endometrial carcinoma was seen only in post menopausal women. Endometrial biopsy
proved to be an effective tool in histopathological characterization of endometrium and can be helpful in avoiding
hysterectomy in AUB.