Introduction: Anaemia in pregnancy is emerging as one of the most important causes of maternal complications, morbidity and offspring mortality in almost all the developing countries of the world including India. Haemolytic anaemia is the anaemia which results from increased rate of red cell destruction. The haemolytic anaemia resulting from intra corpuscular defects are predominantly hereditary in nature. Material and Methods: This is a prospective and descriptive study was carried out on pregnant women with hemolytic anaemias conducted in the Department of Pathology at Tertiary care Teaching Hospital. Inclusion Criteria: Antenatal women (age 18 to 40 years) and Irrespective of gestational age and parity. Anaemias due to other causes (nutritional, blood loss, microangiopathic hemolytic anaemia, acquired hemolysis) were excluded. Hematological parameters were studied using an automated blood cell counter. Result: In our study, 31 women (44.2%) out of 70 persons were within 21-30 year and least were 12 women (17.1%). Of whom 38 were detected to have hemolytic anaemias, 19 had Beta-Thalassemia; 11 had Sickle cell anaemia, 2 had Haemoglobin E Trait. The frequency of Mild to severe anaemia was recorded to be 27.2% to 36.3% sickle cell anaemia, 10.5% to be 39.4% haemolytic anaemia, 47.3% to be 15.7% (β -thalassemia trait), and 100% severe (Haemoglobin E Trait) in pregnant women. Conclusion: Successful outcome in pregnancies complicated with hemolytic anaemias can be achieved with prompt diagnosis, patient education, screening, genetic counselling and prenatal diagnostic testing of foetus and management in a tertiary care hospital by a multidisciplinary approach.