Toxoplasmosis, a parasitic infection with a worldwide distribution, is caused by the protozoan Toxoplasma gondii. This infection can lead to serious health problems when the organism is contracted congenitally or reactivated in immunosuppressed patients. This study included a systematic review and meta-analysis to comprehensively assess the seroprevalence rate of Toxoplasma infection in immunocompromised patients in Turkey. Electronic English and Turkish databases [PubMed, ISI (Web of Knowledge), Google Scholar, Scopus and local databases (Turkish Citation Index and Council of Higher Education (CoHE) thesis center)] between January 2007 and January 2017 were systematically reviewed. Analyses of seroprevalence estimates were pooled using a random-effects meta-analysis. A total of 34 publications, comprising 114496 individuals, were included in the meta-analysis. The most commonly used methods for screening toxoplasmosis in publications were CLIA (chemiluminescence immunoassays) in 13 studies and ELFA in 7 studies. In 4 studies, no information was available about the used serologic methods.