Abstract: The objective of the study was to compare computed tomography (CT) imaging of patients with respect to neurological signs. This is a hospital based prospective observational study. 50 patients of eclampsia (both antepartum and postpartum) were studied. CT scan was performed within 48 hours of admission. Statistical analysis was done chi square test and unpaired student’s t test. In this study, of the 42 cases with CT scan abnormality, 39 women had neurological signs and symptoms and 3 cases did not have neurological signs and symptoms (p=0.000005). The sensitivity, specificity, positive predictive value and negative predictive value were found to be 92.85%, 75%, 95.12% and 66.66 % and the diagnostic accuracy was found to be 90%. CT scan of brain in eclampsia can provide useful intra cerebral information and should be done in cases with severe neurologic manifestations, if possible for every eclamptic mother. Further studies including diagnosis of specific neurological manifestations would emphasize the precise clinical presentations in women with eclampsia. Neuroimaging therefore, will help in modifying management protocol in eclampsia.