Introduction: Induction of labor is an artificial initiation of uterine activity before the spontaneous onset of labor with the aim of achieving vaginal delivery. To assess the effectiveness of extra amniotic saline infusion and prostaglandin E2 gel for induction of labour. Methods: A randomized, comparative study was conducted in the Department of Obstetrics and Gynaecology, Ayaan Institute of Medical Sciences over a period of 6 month. 260 patients at term with a Bishop's score ≤5 with various indications for induction were randomly allocated to group E (extra amniotic normal saline) and group P (PGE2 gel) with 130 women included in each group. Results: 61.5% of Primi delivered within 12 hrs in the extra amniotic saline infusion group compared to only 44.4% in the PGE2 gel group. 96% of Multi delivered within 12 hrs in extra amniotic saline infusion group compared to only 55.6% in the PGE2 gel. The mean Induction delivery interval in Primi with Extra amniotic saline infusion was 12.34 hrs. The mean Induction to delivery interval in Primi with PGE2 gel was 14.43 hrs. The mean Induction to delivery interval in Multi with Extra amniotic saline infusion was 10.54 hrs. The mean Induction to delivery interval in Multi with PGE2 gel was 13.64 hrs. The difference between the two group is statistically significant. Conclusions: Cervical ripening was more effective in the Extra amniotic saline infusion group when compared to PGE2 group. Oxytocin usage was lower in the Extra amniotic saline infusion group when compared to PGE2 gel group.