Corona-virus pandemic has become a major health problem worldwide. It evokes mental health disorders affecting population globally especially the pregnant women and associated with adverse maternal and fetal outcomes. Therefore, we aimed to assess anxiety and depression among pregnant women during this lethal outbreak of corona-virus. We conducted a cross-sectional study at Hamdard University Hospital, Karachi from October 2020 to February 2021. A total of 120 pregnant women were included in this study. Psychological Impact was assessed using questions from DSM-5 Self-Rated Level 1 Cross-Cutting Symptom Measure for Adults and data was analysed using the software IBM SPSS Statistics 26. We found that more than half (67.5%) of pregnant women had developed mental health disorders during this pandemic and there is a need to reform policies for the care and counselling of pregnant women as they are particularly susceptible.