Introduction: Eosinophilia is often identified as part of a complete blood count (CBC) done either routinely or as part of an evaluation for a particular symptom complex. Association of eosinophilia with anaemia most commonly denotes the presence of parasites infection. Parasites relationship with anemia and eosinophilia has been rarely reported due to limited health care access, especially in adult age group. Materials and Methods: A retrospective study was started after obtaining the approval from the ethics committee. Patients with parasitic Infections associated with eosinophilia were correlated with their hemoglobin concentration. This study was conducted during the period of January 2020 and March 2021 in Saveetha Medical College and Hospital, Tamil Nadu. Hematological parameters like hemoglobin, eosinophil count and Absolute eosinophil count were obtained using Sysmex -XN 1000 automated analyser. Results: Out off 83 patients with parasitic Infections associated with eosinophilia, on gender distribution we found 49 were male and 34 were female. 25 patients were anemic and 58 patients were non anemic. On grading of anaemia, according to WHO classification 58 cases were grade 0 (not anaemic), 18 cases were grade l, 6 cases were grade ll and only one case was grade lll. Conclusion: Our study concludes, eosinophilia act as marker for parasitic infections. Degree of anaemia and increased eosinophil count in peripheral blood smear denotes severity of parasitic Infections especially in helminths infection.