Streptococci cause a diverse array of infections. Changing trends in Streptococci causing invasive disease was noticed. This analysis aims to elucidate epidemiological trends amongst various invasive streptococcal diseases (IPD). Surveillance data was abstracted from the Electronic microbiology System for confirmed cases of alpha and Beta-hemolytic streptococci. A total of 91 isolates of streptococci were included. Streptococcus mitis 23 (23.9 %), was the most common isolate followed by Streptococcus agalactiae (Group B) 20 (20.8%) Streptococcus pneumoniae 14 (14.5%) Streptococcus pyogenes (Group A) 7 (7.29%), Streptococcus salivarius 7 (7.29%) and 20other different streptococcal species including (Streptococcus gordonii 5 (5.2%), Streptococcus parasanguinis5 (5.2%), Streptococcus sanguinis 4 (4.1%) Streptococcus species 1 (1%) Streptococcus anginosus 1 (1%), Streptococcus gallolyticus 1(1%), Streptococcus infantarius 1 (1%), Streptococcus intermedius 1 (1%), Streptococcus thermophilus 1 (1%)). Of 91 isolates identified cases of invasive disease, Children ≥1-5 years had the highest incidence for Invasive streptococcal disease (20.4%), Among the IPD, Bacteremia was the most frequently reported clinical manifestation for 64 (70.3%), followed by Invasive soft tissue infection 18 (19.7%) then meningitis 9 (9.8%). There is high prevalence of invasive disease in the study population.