Acidity of α-aryl protons leads to organolithium substitution which actually effects the carbon linked covalently compounds, oxygen, hydrogen, Benz organic compounds and other carbon containing compounds which have carbides, cyanides and carbonates. Chemical solvents are necessary for initialization of chemical reaction in the industry when they react with one another. Organic chemicals are basically manufactured from coal and alcohol in the fermentation industry and they can also be originated from petroleum and natural gas source. Quinones are chemical compounds with aromatic rings and have two ketone substitutions. These compounds are highly reactive and ubiquitous in nature. Removal of hydrogen from hydrocarbon containing hydroxyl group produces an alcohol and it is represented by ROH simply it is called as methanol or methyl alcohol. Nitrogen containing heterocyclic compounds have major role in medicinal chemistry and they play a vital role in the formation of medicines. Silver fluoride reaction such as C-H fluorination reaction produces vicinal position for pyrinides and pyridines which is substitute for nitrogen containing heterocyclic compounds. Sulfinate esters are valuable products and have significant role in structure of medicinal chemistry.