Introduction: Coronary artery disease is the commonest form of heart disease and the leading cause of morbidity and mortality throughout the world. Its prevalence among Bangladeshi has doubled during the past two decades. Myocardial infarction is one of the most common diagnosis in hospitalized patients. Objective: To find out the clinical profile of right ventricular infarction in patients with inferior wall MI. Methods: The study was a hospital based observational cross sectional study. 30 consecutive patients of Inferior wall myocardial infarction as proved by E.C.G. admitted from June 2019 to June 2020 to the ICCU, Department of Cardiology, Al-Helal Specialized Hospital Ltd. Mirpur, Dhaka, Bangladesh. All the Patients were studied at the time of admission, during management in hospital and followed up in the hospital until recovery or death. Criteria only patients with definite evidence of IMI in 12 lead standard ECG were included in this study. For these patient’s additional Right Precordial leads were taken at the time of admission and repeated at 12 hours, 24 hours and 48 hours. Result: Out of the total 150 cases of acute MI admitted in Al-Helal Specialized Hospital Ltd. Dhaka, Bangladesh. The incidence of IMI among all the cases of AMI was 20.0% our study showed a peak incidence of RVI in the age group of 51 – 60 years but the peak incidence of IMI was in the age group of 61 years above. Our study showed a very high incidence of IMI and as well as RVI in males compared to females. This may be due to association of many risk factors which is more common in males. Our study shows percentage of various risk factors associated with MI. In most of cases multiple risk factors co-existed. In our study chest pain was the commonest symptom followed by sweating. Syncope was essentially an important presenting symptom in RVI. Palpitation was the least presenting symptom in IMI. In our study ST segment, ST of RV4 was elevated in all the 15 cases of RVI, ST elevation in all four leads (RV3, RV4, RV5 and RV6) was in 8 cases, ST elevation in any lead in 7 cases and ST of V1 was elevated in 9 cases. The incidence of VF was significantly high in cases of RVI and it was a major cause for mortality. Mortality is significantly high in RVI were as it is lower in IMI without RVI. Conclusion: The incidence of mortality and complications can be reduced only when we are fully aware of the diagnosis and the complications that can occur in RVI. So in all cases of IMI, RVI should be looked for by using simple and specific investigation like RPLs of ECG. Clinically RVI can be suspected when there is bradycardia, irregular pulse, hypotension and elevated JVP with clear lungs in a setting of Acute MI. ECG is a very simple investigative tool. The Advantage of ECG is it is easily available, noninvasive, cost effective, specific and sensitive. Involvement of the right ventricle in inferior wall myocardial infarction significantly affects the mortality and morbidity and complications.