Saudi Journal of Pathology and Microbiology (SJPM)
Volume-3 | Issue-06 | 154-156
Review Article
Oncogenesis: The Role of Virus
Ratna Mouli N, Annet Mary Sabu, Divya Uppala
Published : June 30, 2018
Abstract
Oncogenesis is a very complex and multistep process with many factors
involved. Among the various cancers viral oncogenesis constitutes about 12%. The
human population has been plaqued by viruses particularly viruses with oncogenic
potential. Worldwide, viruses cause numerous miseries ranging from flu to complex
cancers. A noteworthy few among them are caused by oncoviruses such as Human
papilloma virus, Hepatitis B, Hepatitis C, HTLV-1, EBV. Among these viruses Human
papilloma virus and Human T Lymphocyte virus have direct oncogenic potential
whereas HIV, EBV, Hepatitis B and Hepatitis C have indirect oncogenic potential. In
this review, we aim to discuss briefly about the pathogenesis of the most commonly 6
occuring oncoviruses and their oncogenic potential.