Background: Skin lesions are commonly encountered worldwide, but they differ in their clinical presentation depending on demographic region. It is essential to diagnose them correctly as management differs for each. Thus, histopathology is required as a definitive diagnostic tool. Aims and Objectives: To study histopathologic spectrum of non-neoplastic skin lesions, to determine age and sex distribution and analyse the histopathologic subtypes of these lesions. Material and methods: 102 skin biopsies received in the histopathology section of the Department of Pathology of a tertiary care hospital in Northern India were studied over a period of 2 years. 5micron thick sections were done and routine staining with haematoxylin and eosin was done in all the cases. Special stain was applied as and when required. All data was recorded carefully and represented in the form of tables/ charts. Results: A total of 102 skin lesions were analyzed, of which 47.1% were detected in age-group 21-40 years and 64.1% being males. Clinically, hyperpigmented patches/plaques were most frequently encountered. Psoriasis was most common histopathologic diagnosis (39%) followed by Hansen’s disease (17%), with tuberculoid leprosy being the most common subtype. Conclusions: Histopathological examination of skin biopsy remains the gold standard technique for diagnosing a variety of skin lesions. In correlation with clinical history it aids in the accurate diagnosis of the majority of the skin lesions.