In the comparative study of Chinese and English in China, more studies focus on the meaning of words themselves, but less study on the comparison of the pairs of synonyms. Based on the collocative meaning in Leech’s seven types of meanings in semantics, this article will take the Chinese characters “红” “赤”, the English words “red” and “scarlet” as examples to analyze the differences in commendatory and derogatory meanings between Chinese and English synonyms. In this way, we can analyze the linguistic characteristics of the degree to which the Chinese and English are affected by collocative meaning.