Background: Objective structured clinical examinations (OSCEs) are effective clinical evaluation method. In nursing education OSCEs have been used in a limited way with few reports at the graduate level. Objective: This paper is a review of the literature presenting the advantages and disadvantages of using OSCEs in advanced nursing education. Method: Nine studies from advanced practice education and eight studies in undergraduate education were reviewed for advantages and disadvantaged of OSCEs/SPs. Results: OSCEs are objective, valid, reliable and offer opportunities for students to practice wide range of clinical skills. However, OSCEs are expensive and constitute a source of anxiety among students. Nevertheless, students valued the OSCE experience and educators confirmed that its benefits outweigh its cost. Conclusion: The advantages of the OSCEs are greatly supported in the literature. However, OSCEs are better used in addition to, not to replace, the currently used methods.