Introduction: Most people infecting with the SARS-CoV-2 and experiencing mild to severe respiratory illness. Individual knowledge and attitude will improve practices towards covid-19 prevention and precaution measures and it is essential to control the spread of disease. Hence the aim of the study was to evaluate knowledge, attitude and practice towards COVID-19 among undergraduate students as students pays important role in the society. Materials and methods: Cross sectional study was carried out with 60 samples that met the inclusion criteria were selected using convenience sampling technique. Google form was used to collect the data among participants. It contains multiple choice questionnaire regarding demographic variables, knowledge, attitude c, and practice towards COVID-19. The data were tabulated and analyzed by descriptive and inferential statistics. Result: The finding of the study reveals that out of 60 participants, 34(56.67%) had moderate knowledge, 47(78.33%) had favorable attitude and 49(81.67%) had adequate practice through COVID-19 preventive measures. There is a statistically significant positive correlation between knowledge and practice, knowledge and attitude and attitude and practice at the level of p<0.0001. Chi-square test reveals that there is a significantly association between the level of knowledge and practice with selected demographic variables of gender and year of study at the level of p<0.05 and there is no significant association between attitudes with a selected demographic variables. Conclusion: Findings of the present study revealed that, the arts and science college students had generally a moderate level of knowledge, possess a positive attitude, and performed a good practice and active behaviors of preventive measures towards COVID-19. The need to improve the knowledge to promote positive attitude and practice related to updated trends regarding COVID-19. The result of this study may be utilized as a baseline for planning awareness campaigns in the future.