Background: A molar pregnancy is also known as hydatidiform mole which is a benign tumour that develops in the uterus. It begins when an egg is fertilized but normal viable pregnancy not occurs, rather than the placenta develops into an abnormal mass of cyst. In all cases of molar pregnancy observation is essential to detect the reawakening of chorionic activity. Objectives: The aim of the study was to explore the incidence, clinical presentation, management and outcome of the molar pregnancy in our hospital. Materials & Methods: This prospective study was conducted in Faridpur Medical College Hospital, Faridpur, Bangladesh and Bangabandhu Sheikh Mujib Medical University Hospital, Dhaka, Bangladesh. Over a period of one year from August 2005 to July 2006. 50 consecutive patients attended the out-patient’s department (OPDD) of obstetrics & gynaecology and were admitted in the department of obstetrics and gynaecology of these two hospitals during this period, were taken as the study population. All pregnant women who were diagnosed as molar pregnancy were included in the study. Other necessary investigations were done if clinically indicated and to prepare the patient for anesthesia. Statistical analysis of the results was obtained by using window-based computer software devised with Statistical Packages for Social Sciences (SPSS-22). Results: During this period total 6550 pregnant patients and 420 patients with abortion and 85 ectopic pregnancy were admitted in both of the hospitals 50 of them were suffering from gestational trophoblastic diseases. So, incidence of gestrational trophoblastic disease was 7.08 per thousand pregnancies. Conclusion: Results from this study showed that a small portion of patient of molar pregnancy came for routine follow up. To achieve high cure rate and low chemotherapy rate an effective registration programme and treatment protocol should be established.