Abnormal uterine bleeding (AUB) is one of the commonest presenting symptoms in gynaecology out-patient department. The term dysfunctional uterine bleeding is used to describe abnormal uterine bleeding for which no specific cause has been found. Evaluation of histopathological pattern of endometrium is essential for appropriate management of patient with abnormal uterine bleeding. Endometrial biopsy could be effectively used as the first diagnostic step in DUB. This study was done to evaluate histopathology of endometrium for identifying the endometrial causes of DUB. This is a prospective study, undertaken in the department of pathology. This study consisted of 150 cases of hysterectomy specimens and endometrial scrapings received in the department of Pathology, Bhaskar Medical College and Satya Diagnostic Centre, Hyderabad, Telangana State. Total duration of study was 2 years i.e from June 2014 to November 2016. 150 endometrial lesions diagnosed on histopathology were selected for the final analyses. The most common age group presenting with DUB was 40–49 years (49.3%). The commonest pattern in these patients was proliferative endometrium (29.3%),followed by secretory endometrium (14%) and simple cystic hyperplasia (9.3%). Other patterns identified were endometrial polyp, complex hyperplasia without atypia, endometrial carcinoma, pill endometrium ,complex hyperplasia with atypia , endometritis , atrophic endometrium and adenomatous hyperplasia. Endometrial causes of DUB and age pattern was statistically significant with P value <0.05. Histopathological examination of endometrium should be done generously in women presenting with abnormal uterine bleeding especially after the age of 40 years to rule out malignancy. It is useful for diagnosis, to assess therapeutic response and to know the pathological incidence of organic lesions in cases of dysfunctional uterine bleeding prior to surgery.