Motor and cognitive in children growth can be influenced by the practice of football. This study was enhanced with a 10-week game program at three sessions per week, which improved children's performance in motor and cognitive functions. We chose as variables for our study; agility as motor skill and mental flexibility, inhibition and visuospatial memory as cognitive functions. The participants (N = 33) were students in a football promotion center with an average age of 11.5. They were divided into two groups, 16 students from the experimental group who performed a play program and 17 students from the control group who had a regular program. The experimental post-test group showed significantly greater gains than the control group on agility measurements, visuospatial memory, mental flexibility and inhibition. In addition, our results were revealed only a correlation between mental flexibility and agility.