Staphylococcus aureus stays a standout amongst the most much of the time segregated pathogens in both group and hospital practices. The organism form has been observed to be the most widely recognized bacterial agent recuperated from blood circulation system diseases, skin and soft tissue contaminations, pneumonia and healing facility procured post-agent wound diseases. Changes in the example of antimicrobial helplessness of S. aureus and different living beings have been accounted for around the world, particularly in developing countries, making antimicrobial agents progressively less viable in treating bacterial infections. Most strains of the Gram-positive bacterium Staphylococcus aureus are avirulent, anti-infection soft commensals; in any case, in the course of recent decades there have developed various pandemic, harmful, anti-microbial safe strains including methicillin-resistant (MRSA) and vancomycin-resistant (VRSA) strains. This paper presents the review analysis of various studies based on antimicrobial patterns detection of Staphylococcus aureus.