Summary: Due to its impact and its epidemiology, the black Sigatoka disease caused by Pseudocercospora fijiensis is a multidimensional problem, given the insured nutritional and economic importance by the banana and plantain in our region. The limits of existing therapies and especially the inaccessibility to the latter as well as the consequences in the environment and the health lead to the search for new sources. It is in this framework that this work has focused on the evaluation of the antifungal activity of extracts from 14 plants used in traditional medicine against fungal infections of the human resources in the Kisangani region. It has been tested by the method of inhibition of the growth of the mycelian explantant on Potato Dextrose Agar (PDA) medium in a Petri dish. The main results obtained show, after the evolution of the diameters of growth of mycelian explantants on media containing different extracts compared to the diameter of the light during the incubation period, that all plants tested have antifungal effects at different levels and/or moments during the incubation. And these effects have been observed either during the entire incubation period, or at the beginning of the incubation, or toward the end of the incubation, or only slowed growth in relation to the witness without as much completely inhibiting it. Carica papaya has been the only plant having kept its inhibitory effect complete for all forms of extracts tested.