A cross-sectional study of gastrointestinal helminthes parasites of equine was conducted for 6 months from November 2013 to April 2014 in and around Gondar, to determine the prevalence and associated risk factors of helminthes parasites of equines. A total of 384 faecal samples (donkeys (n=238), horses and (n=146) were collected from randomly selected equine for coproscopical examination and 40 pooled samples for recovery of parasitic larvae were collected and processed in Gonder University Veterinary Parasitological Laboratory. The overall prevalence of gastrointestinal helminthes parasite was 97.4% (374/384) out of which, 28.12% were mixed infections, with the prevalence rate of 97.9% and 96.6% in donkey, and horse, respectively. Coprological examination revealed the existence of five species and four genera of helminthes parasite namely, Strongylus species 47.13 %, Cyathostomes 22.65% Trichostrongylus axei 8.07 %, Triodonthophorus species 6.77%, Parascaris equorum5.2 %, Oxyuris equi 3.12 %, Strongyloides westeri 1.56 %, Anoplocephala species 1.04 % and Gastrodiscus species 1.82 %. No significant variations(P>0.05) in prevalence of helminth parasites were noticed in relation to species, age, body condition score and sex groups of equine, except in case of Parascaris equorum in which prevalence was observed to significantly decrease and increase with age, respectively (P<0.05). The average egg per gram of faeces in this study was 114.7 with a range of 100 to 5,500. The copro-culture study revealed that Strongylus vulgaris, Strongylus edentates and Cyathostomes were the major helminths larvae identified in the area during the study period. Generally parasitism and poly parasitism were the common finding of this work. Equine diseases in general, parasitism in particular, should be given attention in the region where equines are practically participating in all agricultural activities, from tillage to harvest.