Pemphigus vulgaris and mucous membrane pemphigoid are uncommon dermatological disorders which also involves the mucosae of the oral cavity. Both the conditions differ in microscopy and prognosis. Thus the aim of the present paper is to present one case each of pemphigus vulgaris and mucous membrane pemphigoid with oral involvement. Special attention has been made on the clinical tests to evaluate these disorders and cytological pitfalls, which may be helpful for both clinicians and pathologists.