Since the outbreak of coronavirus disease 2019 (COVID-19) in late December 2019, it has brought significant harm and challenges to over 200 countries and geographic regions around the world. COVID-19 affects people in different ways, with patients exhibiting a range of symptoms and severity. Risk factors such as age, gender and comorbidities have been highlighted as increasing the risk of complications and mortality. These risk factors, however, do not account for the other 52% of deaths arising from COVID-19 in seemingly healthy individuals. This review examines the interplay between periodontal disease and development of severe complications of COVID 19. Periodontal infections alter the natural course of systemic conditions, due to the presence of a constant low grade systemic inflammatory state in the body. Correlating these two entities is the main focus of this review and how maintaining good oral health may reduce the risk of complications of COVID-19.