The study of the topic aims to clarify some theoretical issues about drugs and drug trading, the contents of current legal regulations on drug trading conditions, and practical application in Dong Nai province. On that basis, we can see the problems and shortcomings of the current law and propose a number of solutions to improve and improve the effectiveness of the application of the law on drug trading conditions in Vietnam in general and Dong Nai province in particular. To achieve that goal, this study focuses on the following contents: Analyzing the practice of drug trading in Dong Nai province, on that basis pointing out the limitations and shortcomings in the implementation of the law on drug trading lawsuits; analyzing the current legal status of drug trading conditions to point out inadequacies in the provisions of the law on the stated issue; provides a number of orientations, specific solutions, and recommendations to improve and improve the effectiveness of the application of the law on drug trading conditions.