Nurses in all part and site can establish leadership in contaminating prevention and control using the knowledge skills and site judgment to initiate proper and immediate infection control nurses play a very important role in infection control. Health care professionals in certain are often showing to several infections healing their daily work nurses have complete awareness and infection control practice. All health care workers whose responsibility to protect the patients from getting infection in hospital and other health care center. Keeping an infection free setting patient’s recovery will be promoted and provide the great quality of care. Nurses can do a great agreement to communicate effectively e.g. Nurses should provide the information charge nurses visitors and patient. Provide the proper information patient how to protect themself including support staff in team. Nurses contribution in this war against infection control using the barrier precaution like face marks caps gowns and gloves. Infection control and prevention practices minimize the infection to apply the patient care use the standard Precautions the practices are protect and prevent to spread infections among patients and healthworker and nurses. Frequently hand washing, use of proper personal protective measures sharp safety respiratory care and hygiene good practices of safe injection and use the sterilized instruments. Nightingale mentioned the person as a patient. Atmosphere affects the person. Better atmosphere help to heal the patient soon as compared to polluted. Health is the complete well-being not only to be well. Good environment provide healthy life and prevent the disease.