Plants have defensive proteins to survive in drought and heat conditions by activation extensive stomata systems. Different factors affected the plant growth such as drought as one of major cause in seed growth inhibition. Biotic as well as abiotic stresses cause changes in morphology and also involve at the molecular alteration or activations of certain genes. Adverse effects of high temperature on cereal crops vary with the timing, duration, and sternness of the heat stresses. Harmful mutations that have drastic effects tend to be fixed in modern breeding pools. Drought also affects the growth of certain growth promoting factors also on turgor. It leads to problems in transport of water to different parts of plants such as xylem and other cells that playing significant role in prompting the plant growth. Different techniques and software’s are currently available to under table the nature, type and function performed by each gene in biotic and abiotic stresses. Microarray as one of the best technique used for the gene expression in the plants thus helping the rescuing of disease rate in plants. Different genetic traits have been placed in special groups in order to communicate the stress groups of plants in relation to environment. Different genes are activated under stress conditions that can be potentially recognized and sequenced at the genomics level due to different methods of sequencing used for checking their specific sequence of genes.