Camellia sinensis (Lipton tea) contains polyphenols responsible for antioxidant, antidiabetic and anticancer effects. Citrus aurauntifolia is one of the major fruit trees that grows throughout the world and is known for its refreshing juice and health benefits. Some attributes of Citrus aurauntifolia (Lime) include pharmacological properties such as antitumor, anti-inflammatory, and anti-obesity activities. Lime contains phytochemicals such as flavonoids, pectins, vitamin C and vitamin E. The study was aimed at determining the effects of the decoction of lime and lipton tea on plasma glucose concentration and weight of normal albino rats. Twenty four (24) female albino normal rats of average body weight of 150g were randomly placed into two (2) groups of twelve rats each. The plasma glucose concentration was determined by spectrophotometry. The result showed that the plasma glucose decreased significantly (p<0.05) in test group compared to the controls. The rats in the test group experienced some weight loss compared to the control group with no statistical significance (p<0.05). The histological report showed that the decoction of lime and lipton tea, affected the liver, kidney adversely but had no effect on the heart after two weeks of administration. The decoction of lime and lipton tea in moderate dosage can be clinically significant in the reduction of high plasma glucose levels, hence may be beneficial in the management of diabetes mellitus.