Scholars carrying heavy backpacks incur misaligned vertebral posture and neuro-musculoskeletal discomfort and pain. This report intends to determine whether there is a compensatory inverse relationship between standing anterior pelvic tilt (SAPT) and craniovertebral angles (CVA) when heavy backpacks are carried. A male pubescent carried a backpack weighing 6.2kg (17.3% of his body mass) over both shoulders resting against his vertebral column. The pubescent CVA, SAPT, standing vertex height (SVH) was measure during unloaded, and three loaded phases. Each loaded phase approximately increased from 10%, 20% and 30% of the pubescent’s relative body mass. The incremental backpack masses reduced the SVH and increased the SAPT, while simultaneously reducing CVA. There was a positive relationship between increased backpack mass and SAPT (r=+0.9). Craniovertebral angle inversely attenuated in response to the heavy backpack loads (r=-0.9). These findings indicate that there is an inverse compensatory relationship between SAPT and CVA when carrying heavy backpacks.