The study investigated factors influencing E-learning in Tertiary Institutions in Rivers State, Nigeria. Three research questions guided the study. The study adopted a descriptive survey research design. A sample of 376 undergraduate students was drawn from the population of 3,660 students in the Faculty of Education of three tertiary institutions in Rivers State through proportionate stratified random sampling technique. An instrument titled E-learning Factors Influence Questionnaire (EFIQ) which was developed by the researchers was used for data collection. It contained 23 items which are in three sections of A-facilities, B-lecturer’s competencies, C-students attitude. The EFIQ was validated by experts in Educational Technology and Measurement and Evaluation based on face and construct validities. The reliability of the instrument EFIQ was established through Cronbach Alpha technique and the reliability coefficient obtained was 0.82. Data collected was analyzed using mean and standard deviation, and a criterion mean of 2.50 was used for judgement. The result revealed that facilities, lecturer’s competencies and attitude of students influence E-learning in tertiary institutions in Rivers State. Based on these results, recommendations were made including that students should endeavour to have positive attitude towards e-learning and the tertiary institutions should provide enough e-learning facilities which will aid the students in learning.