Palpable breast lumps in females are quite common which can be benign or malignant. After carcinoma cervix, carcinoma breast is the second most common cancer in females. Rapid diagnostic test like Fine needle aspiration cytology (FNAC) which is easy, quick, reliable, affordable and an OPD procedure can be utilized to plan the treatment accordingly. In this study various breast lesions of Pre-menopausal females were evaluated on the basis of cytological findings. This two-year study from January 2013 to December 2015 including 200 cases aspirated from palpable breast lumps of pre-menopausal females. Physical examination of breast lumps was done by palpation with aspiration and Cytological diagnosis was made. In this study most common benign breast lesion was fibroadenoma and among malignant ones medullary carcinoma was predominant (02 cases)