At present, domestic vocabulary teaching, including academic English vocabulary teaching, mostly adopts traditional teaching methods. The current situation is that students with limited academic vocabulary have low academic competence. It is English teachers who have the duty and responsibility to help students expand their academic English vocabulary. Guided by the Production-oriented approach (POA), this article manages to construct the teaching design of academic English vocabulary teaching and explores effective ways to enhance students’ academic English proficiency. This article finds that under the guidance of POA theory, academic English vocabulary teaching can more effectively stimulate students’ internal motivation, promote the completion of production tasks, enhance students’ sense of acquisition, and more accord with China’s foreign language teaching practice.