Saudi Journal of Pathology and Microbiology (SJPM)
Volume-6 | Issue-01 | 19-22
Original Research Article
Prevalence of Hepatitis A Virus (HAV) and Hepatitis E Virus (HEV) In the Patients Presenting With Acute Viral Hepatitis at a Tertiary Care Hospital, Rajkot, Western India
Dr. Nirali Daftary, Dr. Dipika Patel
Published : Jan. 9, 2021
Abstract
Acute viral hepatitis (AVH) is a systemic infection affecting the liver predominantly. It is a major public health problem in India and other developing nations having inadequate sanitary conditions. This study was undertaken to determine the trends of Hepatitis A & E & their coinfection in a tertiary care hospital so that appropriate management of cases as well as prevention can be planned. Material & Methods: Over a 1-year period, a total of 1074 serum samples were collected from clinically suspected cases of hepatitis. The serum samples were screened for IgM anti-HAV and IgM anti-HEV. Seasonal variation & age group wise seropositivity of hepatitis A& E was studied. Results: Out of the total 1074 samples screened, the percentage positivity of Hepatitis A was 6% and Hepatits E was 15% respectively. Of both Hepatitis A & E positive cases, males outnumbered females. Majority of HAV positive cases were children whereas majority of hepatitis E positive cases were adults. Conclusion: The prevalence of HEV was more than HAV in enterically transmitted viruses, making them a major public health problem in our area. Seasonal trends of infection were observed in addition, co-infection though infrequent, but still detected in one case.