Infection with the SARS-Cov-2 virus induces an unusual pre-thrombotic state, of multifactorial origin, responsible for a high incidence of venous thromboembolic events but also of arterial thromboses which have a negative impact on the prognosis of patients. Knowledge of the mechanisms of thrombosis formation has improved significantly since the onset of the pandemic pending appropriate protocols for preventive and curative anticoagulant therapy during COVID 19, emerging from randomized controlled clinical trials. We report the case of a young patient hospitalized with a moderate form of COVID 19 who presented with pulmonary embolism and acute ischemic stroke related to internal carotid thrombosis.