Abstract: Medical professionals around the world are facing new challenges day in and day out. With the ever-growing advances, the ever-expanding populations and ever complicating life issues, doctors are expected to in their best order and shape at every snap shut of time. This review highlights the principles of medical professionalism. Literature search strategy included electronic database searches, internet searches, hand searching, ancestry searching and networking. The new aspects of medical professionalism are providing a framework within which doctor duties towards the patients are being met with the enhancement with doctor qualities. So much accentuation nowadays is made on patient’s autonomy and confidentiality. In this review, these aspects of the professionalism are being discussed.