Abstract: Necrotizing fasciitis infection (NFE) is a disease characterized by the rapid spread of necrosis of soft tissues and fascias and can be mortal if not properly treated. Predisposing factors include immunosuppressive factors such as diabetes mellitus, alcoholism, liver cirrhosis, hypertension, chronic renal failure and malignancy. Necrotizing fasciitis is rarely localized in the head and neck region. In this study; we presented a case of necrotizing fasciitis in neck region, which we had followed in our clinic with predisposing factors of diabetes and chronic renal failure.