Abstract: Malaria is a major public health problem. In India, Malaria is the disease is responsible for very high morbidity and mortality. The Government has got the larger responsibility in controlling the Malaria; with the community involvement is necessary, so that the urban slum adults need Health education programme to reduce the incidence of Malaria and for the prevention of Malaria. This study was conducted to evaluate the effectiveness of STP on prevention of Malaria. A quasi experimental single group pretest posttest research design was used to evaluate the effectiveness of structured teaching programme on Malaria prevention at selected urban slum area of Gwalior city. The study was conducted on 50 adults selected by purposive sampling techniques. Tool was developed validity and reliability was calculated, after conducting pretest PTP was introduced and then posttest was done. The findings of the study shows that mean posttest knowledge score (19.54) of the subjects was higher than the mean pretest knowledge score (11.72), hence PTP on malaria prevention for adult was effective. After the detailed analysis of this study shows that PTP for Malaria prevention was very effective and could also are used for other setting and for other community setting.