Introduction: Stroke patients with haemorrhagic and ischemic strokes were compared with regard to stroke severity, mortality, and cardiovascular risk factors. Material and Methods: This prospective and descriptive study was done during January 2019 and September 2020. This case-control study was conducted on an overall population of 120 individuals (40 haemorrhagic, 40 ischemic strokes and as the case groups; 40 healthy individuals as the control group). The diagnosis was made by the clinical examination and brain CT scan. Our excluding criteria were a previous history of a cerebrovascular event, history of a recent infectious or inflammatory disease, cancer, autoimmune disorder, haematological disorder, renal or hepatic disease, or use of immune-suppressive or anti-inflammatory drugs in the previous two months. Result: A total of 120 individuals (40 haemorrhagic strokes and 40 ischemic strokes as the case groups; 40 individuals as the control group) were identified during the study follow-up. The increase in MDA in ischemic stroke (ISPs) and Haemorrhagic stroke patients is highly significant (P < 0.001) when compared to control subjects. This indicates that lipid peroxidation is significantly increased in ISPs and the increase in MDA is more in ISPs than haemorrhagic stroke patients (p<0.001). Similarly, nitric oxide levels are also increased in both ISPs and HSPs. GPX levels are decreased significantly in ISPs and HSPs compared to control subjects(p<0.001). Maximum decline in GPX is found in ISPs with HSPs (p<0.001). The Uric acid levels are significantly increased in ISPs and HSPs when compared to control subjects (p<0.003) and the increase is more in ISPs with HSPs (Table 3). The SOD levels are decreased significantly (p<0.05) in ISPs and HSPs when compared to control subjects, whereas its levels are slightly decreased in ISPs with HSPs. Similarly, Catalase levels also decreased in both ISPs and HSPs. Conclusion: Hence, showed a direct positive correlation with infarct size (Ischemic stroke) but less in hemorrhagic stroke when compared with the control group. The antioxidative parameters like Catalase and superoxide dismutase were decreased both ischemic and hemorrhagic stroke when compared with control.