Abstract: In the middle-late stage of reservoir development, in order to sovle the problem of describing sand body boundary between wells, river channel’s combination is diversity, difficult to describe the variation sand body’s distribution, and so on. We elaborate geological interpretation and level calibration Sartu oil-bearing layer, under seismic sedimentology’s guidance, we use strata slice technology to extract seismic attribute, after that we choose seismic attribute slice of every sedimentation unit quantitative and qualitative, use coherence technique as an auxiliary method to describe sand body boundary, at last we make amplitude-coherence fusion slice, and combined with log information, the study of describing sand body of thirty-three sedimentation unit Sartu oil-bearing layer has been carried out. The study shows that amplitude-coherence fusion slices have a great effect on the problem of describing sand body boundary between wells, river channel’s combination is diversity and describe the variation sand body’s distribution, and we continue forecasting the sand body’s distribution at the lower sedimentation unit which has no log information in the north of the study area, and solve the problem of only use log information to describe sand body before.