Despite the status of English as dominant language in Nigeria, a lot is still required to enhance its effective teaching and learning. Being a second language in Nigeria, English is confronted with difficulties faced by students, teachers, and researchers of the language. This raises a need for professional based English teaching. It is on this note that this paper reviewed different strategies developed by different scholars in the teaching of ESP vocabulary under the framework of Communicative Approach to language teaching. The paper observed that the teaching ESP vocabulary in Nigerian context requires a combination of methodologies and concluded that lecturers of ESP should utilize methodologies that encourage interactive use of the target vocabulary. The paper recommended that individual lecturers should experiment with various strategies and choose any combinations they find most suitable for both their learners and the teaching circumstances.