Saudi Journal of Biomedical Research (SJBR)
Volume-4 | Issue-08 | 295-303
Original Research Article
Effect of Toxoplasma Gondii Infection on Haematological and Liver Function Parameters among Abortive Women in El-Beida City
Alla H Hassen, Marfoua S Ali, Ahmad M Ekhnafer
Published : Aug. 30, 2019
Abstract
This work was carried out to investigate the changes in haematological and some of liver function parameters among
abortive females after diagnosing toxoplasmosis-related symptoms in El-Beida City, Libya. Eighty seven abortive
women during the period from October 2018 to March 2019 were chosen as a study group. These women were split into
two groups when the antibodies of Toxoplasma was present. (IgG and/or IgM) (44 cases who positive with
toxoplasmosis). The largest incidence was observed in age group 21-25 years followed by age groups 31-35 and 26-30.
While the smallest incidence was observed in the age group, more than 46 years followed with age groups of less than 20
years. At age group 41-45, percentage of positive toxoplasmosis was found higher than negative toxoplasmosis. All
positive cases, 50.6% of them was found to have IgG anti-toxoplasma antibodies sero-positive. 13.6% of total cases was
mixed seropositive for IgG and IgM. These value of antibodies IgG/IgM were found statistically difference between
positive and negative toxoplasmosis. Only, the mean corpuscular volume (MCV), mean corpuscular hemoglobin (MCH)
and white blood cell count were decreased significantly in positive toxoplasmosis. Mean values of RBC count, HGB
concentrations, percent of hematocrit (HCT), mean corpuscular hemoglobin concentration (MCHC) and red blood cell
distribution width (RDW) were not statistically different in positive compared to negative cases. Lymphocytes (Lymph
%) and mid cells total count (MID %) were increased and granocytes (Gran %) decreased slightly in positive
toxoplasmosis without significantly deference. Meanwhile the mean platelets number (PLT) the volume occupied by
platelets in the blood (PCT %), the mean platelet volume (MPV %) and platelets distribution width (PDW %) were
changed without significant deference. In terms of blood group, the smallest incidence was discovered with blood group
O and the largest incidence with blood group AB. The highest prevalence among individuals with blood group who have
Rh-positive at same blood group. The mean levels of AST, ALT and ALP in the serum of the positive toxoplasmosis was
decreased without significantly deference. These results were might give a better understanding about pathogenesis of
toxoplasmosis.