Introduction: Snake bite is a significant cause of mortality and morbidity in tropical and sub-tropical countries. Snake venom is a complex mixture containing peptides, polypeptides, enzymes, glycoproteins and other substances which have pharmacological properties. It mainly affects the vital organ systems such as the cardiovascular, nervous, renal and respiratory systems. Studies have shown that following the bite krait snake, patients suffer from hypokalemia and sink into coma. However, no clear conclusive result has been arrived at in studies conducted in rural Kolar district. Objective: To explore the biochemical changes with respect to renal disturbances in snake bites. Methodology: This is a hospital based observational study since these parameters were studied after the snake bite and at the time of admission; data was collected from our hospital records and includes the measured values of blood urea, serum creatinine, serum sodium and potassium levels, bleeding time and clotting time at the time of admission in 30 snake bite victims. These cases were compared with age and gender matched healthy controls. Results: Blood urea and serum creatinine levels were not elevated in the victims while serum potassium level was decreased (p<0.001) and serum sodium was increased (p<0.05). Bleeding time was also increased (p<0.001) when compared to controls. Conclusion: The hypokalemia observed may be due to increased urinary excretion or intracellular shifting of potassium.