Generalized lymphadenopathy is a common cause of concern for both patients and clinicians. Causes for kikuchi fujimoto’s are infections and malignancies. Kikuchi Fujimoto disease (KFD) presents with fever, lymphadenopathy it also presents with systemic involvement. We report the cases of a 5 patients who presented with generalized lymphadenopathy, high fever, skin vasculitis and polyserositis. The lymph-node biopsy shows histiocytotic necrotizing lymphadenitis, suggestive of Kikuchi’s disease.