The aim of present work is to develop simple, economic, precise and cost-effective UV spectrophotometric method for determination of Nevirapine, an anti-retro viral drug, in bulk and pharmaceutical dosage form. Forced degradation is a degradation of new drug substance and drug product at conditions more severe than accelerated conditions. Forced degradation studies show the chemical behaviour of the molecule which in turn helps in the development of formulation and package. The method for Nevirapine was developed using methanol and water and absorbance maxima was found to be at 282nm with a correlation coefficient of 0.9978. Forced degradation studies of Nevirapine like Acid degradation, Base degradation, Thermal, Photolytic, and Peroxide was conducted in UV Spectrophotometer using methanol and water and percentage degradation was calculated.