A total of 223 pap tests done on women who attended the outpatient ward for follow-up visits after posthystrectomy for malignant and benign indications between the years 2015 to till date in Mamata Medical College, Khammam and Mamata academy of medical sciences, Bachupally Hyderabad. Each woman under investigation had a clinical history, gynecological examination and a sample collected from the vaginal vault by using cytobrush or Ayres’s spatula for preparing the Pap smear in the pathology department to study the vaginal vault cytology. A vaginal biopsy was also taken in possible cases for histopathology. Aims and objectives: Early detection of invasive and pre-invasive lesions in the vaginal vault in post hysterectomy patients by using Pap test as a Primary screening procedure. To determine the use and effectiveness of Pap smears in detecting Recurrent and primary malignant lesions on vaginal vault samples in post-hysterectomy patients.