Biofouling particularly micro-fouling is a very complex phenomenon to understand. This present work is carried out to understand the influence of wood type on the development of microfoulers. The panels were constructed by using commercially important hard wood such as Tectona grandis, Pterocarpus Sp, Thespesia populnea and Mangifera indica. The assembled panels were immersed and studied for the period of 21 days in velar estuary, Porto-Novo. The result shows that the settlement of microfoulers are high on the panel constructed by Mangifera indica (89 X 10-5 CFU/cm2) and low on the panel constructed by Pterocarpus Sp (71 X 10-5 CFU/cm2). Thus, the selection of materials for the marine structures must be heedful and well established to prevent the loss due to the fouling process.