Coronavirus disease 2019 (abbreviated “COVID- 19”) is a highly contagious respiratory disease. It was first detected in December 2019 in Wuhan, China and since then it has spread across the globe and leads to many mortality and morbidity [1]. Therefore strict lockdown and many unprecedented measures have been adopted to control the rapid spread of the COVID-19 across the world. The effectiveness of these measures is highly dependent on cooperation of all members of society. People’s adherence to preventive measures is markedly affected by their knowledge, attitude, and practices (KAP) towards COVID-19. Health care professional should have correct knowledge and fair attitude towards COVID-19, since they are the most influential community in health matters. In this study, KAP towards COVID-19 among the B.Sc. nursing students of Saudi Arabia was assessed. An online KAP questionnaire was answered by the participants. The questionnaire consisted of 15 knowledge, 10 attitude and 5 practice based questions. The average knowledge score for participants was 10.8. The overall correct answer rate of the knowledge questionnaire was 72%. About 64% of participants were obtained scores above 10. The majority of the respondents 72.6% were hopeful that world people will get rid of COVID-19 very soon, 79% believe that hand hygiene and wearing a mask can help to prevent getting the infection, 90.3% agree that practicing quarantine by staying at home and avoiding crowded places can help prevent getting infection, 75.8% conscious about the guideline given by WHO, 88.7% agree that it is necessary to rub hands with soap or alcohol for at least 20 seconds, 96.8% agree that it is essential to maintain at least 1 meter physical distance to prevent getting infection, 71% believe that humanity, fraternity and empathy to one another help us fight against COVID-19, 74.2%believe that focusing on improving immune power is a good option to prevent getting infection, 38.7%think that COVID-19 will remain in the world forever, 48.4% believe that people those are already recover from the disease also cannot transmit infection to others, 77.4% wash their hands frequently with soap and water for at least 20 to 40 seconds, 91.9% follow social distancing to avoid contact of infected persons, 83.9% avoid going crowded places these days, 75.8% practicing good respiratory hygiene and avoiding touching the eyes, nose or mouth with unwashed hands and 87.1% wore masks when going out in recent days. There was no significant difference found between the knowledgeable score of males and females about COVID-19. They hold optimistic attitudes, and have appropriate practices towards COVID-19.